Blood, Bone and 3192 Images

FESCH.TV INFORMIERT:

This video showcases the hind limb of a special strain of guinea pig that spontaneously develops osteoarthritis with age, just like us!

The femur is at the top and the proximal tibia is on the right. These bones are surrounded by muscle (green) and blood vessels. A glowing red tracer can be found in both the blood vessels and bone marrow; we use this tracer to investigate how osteoarthritis affects the travel of molecules from (and between) the blood and bone, as well as the entire joint. Through our work, we’ll be able to develop new treatments for osteoarthritis.

This video moves through 3192 individual images that have been stitched together and represents 43+ hours of continuous imaging on a microscope.